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Deep, specific next-era sequencing has revealed that subclonal mutations (i.e., These present in only a fraction of tumor cells) can be detected for all driver genes and are related to fast condition progression and bad end result.11–13 This is particularly suitable for TP53
mutations, shed their destructive influence in patients taken care of with VO. The only component that remained predictive of a shorter progression-free of charge survival In this particular cohort of individuals was TP53
The proposed technique calculates the closest beacon b y statistical strategy. The positioning is calculated by RSSI that is processed through filtering and statistical check. This paper experiences an indoor positioning procedure working with the nearest beacon and evaluates the system.
mutations and complex kar yotype. It follows a linear evolution in the CLL clone with the recurrent acquisition of CDKN2A
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